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Scientific studies show that fast actions to reduce near-term warming are essential to slowing self-reinforcing climate feedbacks and avoiding irreversible tipping points. Yet cutting CO2 emissions only marginally impacts near-term warming. This study identifies two of the most effective mitigation strategies to limit near-term warming beyond CO2 mitigation, namely reducing short-lived climate pollutants (SLCPs) and promoting targeted nature-based solutions (NbS), and comprehensively reviews the latest scientific progress in these fields. Studies show that quickly reducing SLCP emissions, particularly hydrofluorocarbons (HFCs), methane, and black carbon, from all relevant sectors can avoid up to 0.6 °C of warming by 2050. Additionally, promoting targeted NbS that protect and enhance natural carbon sinks, including in forests, wetlands, grasslands, and agricultural lands, can avoid emissions of 23.8 Gt of CO2e per year in 2030, without jeopardizing food security and biodiversity. Based on the scientific evidence, the paper provided a series of policy recommendations on SLCPs and NbS.